---
title: "AlphaFold DB (Predicted Protein Structures)"
description: "| Endpoint | Description | |----------|-------------| | `/prediction/{uniprot_accession}` | Prediction metadata by UniProt ID |"
type: skill
canonical_url: https://claudary.paisolsolutions.com/skills/alphafold
source: "Claudary"
difficulty: intermediate
author: "Claude Code Knowledge Pack"
date: 2026-07-10T11:07:29.195Z
license: CC-BY-4.0
attribution: "AlphaFold DB (Predicted Protein Structures) — Claudary (https://claudary.paisolsolutions.com/skills/alphafold)"
---

# AlphaFold DB (Predicted Protein Structures)
| Endpoint | Description | |----------|-------------| | `/prediction/{uniprot_accession}` | Prediction metadata by UniProt ID |

## Overview

# AlphaFold DB (Predicted Protein Structures)

## Base URL
```
https://alphafold.ebi.ac.uk/api/
```

## Auth
No auth required.

## Key Endpoints

| Endpoint | Description |
|----------|-------------|
| `/prediction/{uniprot_accession}` | Prediction metadata by UniProt ID |

## Structure File URLs (direct download)
```
https://alphafold.ebi.ac.uk/files/AF-{UNIPROT}-F1-model_v4.pdb
https://alphafold.ebi.ac.uk/files/AF-{UNIPROT}-F1-model_v4.cif
https://alphafold.ebi.ac.uk/files/AF-{UNIPROT}-F1-predicted_aligned_error_v4.json
```

## Example Calls
```
# Get prediction metadata for EGFR
https://alphafold.ebi.ac.uk/api/prediction/P00533

# Download PDB structure
https://alphafold.ebi.ac.uk/files/AF-P00533-F1-model_v4.pdb

# Download PAE (predicted aligned error)
https://alphafold.ebi.ac.uk/files/AF-P00533-F1-predicted_aligned_error_v4.json
```

## Response Format
JSON for metadata. PDB/mmCIF for structures. PAE as JSON matrix.

## Rate Limits
No strict limits. Use FTP/Cloud for bulk downloads (~200M+ structures).

---

Source: [Claudary](https://claudary.paisolsolutions.com/skills/alphafold) · https://claudary.paisolsolutions.com